Antiviral therapy and hepatocellular carcinogenesis
نویسندگان
چکیده
منابع مشابه
Does antiviral therapy prevent hepatocellular carcinoma?
Chronic infection with HBV or HCV can lead to the development of hepatocellular carcinoma (HCC). The major risk factors for HBV-related HCC are persistent presence of hepatitis B e antigen (HBeAg) and/or high serum HBV DNA levels, and cirrhosis. The major risk factor for HCV-related HCC is cirrhosis. One randomized double blind controlled trial of lamivudine in patients with HBeAg and/or high s...
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Hepatocellular carcinoma (HCC) is a highly prevalent and lethal cancer worldwide; despite the curative treatment for HCC, the rate of tumor recurrence after hepatectomy remains high. Tumor recurrence can occur early (<2 years) or late (>2 years) as metastases or de novo tumors. Several tumor factors were associated with HCC recurrence; high hepatitis B virus (HBV) load is the major risk factor ...
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this report describes a 66-year-old male who had a long history of hepatitis b virus (hbv) infection. he was found hepatocellular carcinoma (hcc) 5 months after lamivudine resistance mutation and then received a successful hepatectomy. three years later, hepatitis b envelope antigen seroconversion was achieved and nucleoside analogs were discontinued. after the withdrawn of antiviral treatment,...
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Hepatocellular carcinoma (HCC) has had a continuous increase worldwide in incidence over the last two decades. The development of HCC has a complicated process and correlates to numerous risk factors including hepatitis virus infection, alcoholism, food toxins, diabetes, obesity, smoking, congenital liver diseases, and errors of metabolism. Molecular links are also identified, which characteriz...
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ژورنال
عنوان ژورنال: Cancer
سال: 2015
ISSN: 0008-543X
DOI: 10.1002/cncr.29696